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    Home / News / Hoskinson Bets Big on Cardano, Bitcoin DeFi, and Healthcare
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September 11, 2025 by Imelda
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Hoskinson Bets Big on Cardano, Bitcoin DeFi, and Healthcare

Charles Hoskinson, the founder of Cardano, is once again making headlines with big ideas—not just in crypto, but also in healthcare.

He’s currently working on two major things. First, a $200 million healthcare project in Gillette, Wyoming, which aims to completely change how people receive medical care. Second, he’s making bold predictions about the future of decentralized finance (DeFi), especially how Bitcoin-based DeFi could eventually outshine Ethereum.

Cardano was once one of the top three cryptocurrencies, especially after it introduced smart contracts in 2021. But the hype didn’t last long. Developers found Cardano too strict and hard to build on, so many switched to faster and easier platforms like Solana. While Cardano focused on being secure and stable, it lost some momentum because it lacked flexibility.

To fix this, Cardano has now opened its doors to more common programming languages like Rust and TypeScript. This change is meant to attract developers and bring fresh innovation back to the platform.

Hoskinson is also openly critical of Ethereum. He says Ethereum relies too heavily on layer-2 solutions, which could cause problems like losing liquidity and users. He believes that once big institutions get involved in crypto, Bitcoin DeFi could grow even larger than Ethereum’s entire market cap. He thinks platforms like Cardano and Stacks are better suited for that future.

Outside the crypto world, Hoskinson is trying to revolutionize healthcare. His Wyoming clinic will use AI, patient-friendly systems, and blockchain privacy tools like zero-knowledge proofs. The goal is to create an open-source healthcare model that other places around the world can copy and improve on.

Cardano may not be as popular in the news as it used to be, but activity on the network is rising again. Futures open interest recently hit $2.5 billion—levels not seen since 2021. Also, over $4 billion worth of on-chain transactions happened in just one week.

All of this shows that Cardano is still very much in the game. Hoskinson continues to bet big—not just on blockchain technology, but also on changing how the world works, from finance to healthcare.

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